4-butylresorcinol is a highly effective skin whitening and brightening agent, which has an important inhibitory effect on tyrosinase activity and plays a synergistic whitening effect in the process of melanin synthesis. It can inhibit melanosis, fight against melasma and freckles, and has anti-ultraviolet effect.
English name 4-Butylresorcinol
CAS number 18979-61-8
Molecular weight 166.217
Density 1.1±0.1 g/cm3
Boiling point 300.7±12.0 °C at 760 mmHg
Molecular formula C10H14O2
Flash point 144.5±14.2 °C
The function of 4-n-butylresorcinol
1. Tyrosinase inhibitors:
4-n-butylresorcinol can effectively inhibit the activity of tyrosinase, 1 which is a key enzyme in melanin synthesis. By interfering with the tyrosinase synthesis and glycosylation process, it prevents the enzyme from being absorbed by melanosomes, thereby reducing melanin production.
2. Whitening agent:
It acts as a potent skin lightening agent and is able to reduce pigmentation, especially against melasma caused by sun exposure 1. By acting in the three stages of melanin synthesis, it not only inhibits tyrosinase activity, but also collaborates with the whitening process.
3. Anti-saccharification effect:
Studies have shown that 4-n-butylresorcinol has anti-glycation effects,
which may help slow down the skin aging process.
4. Light stripping effect:
Under certain conditions, 4-n-butylresorcinol, when used in combination with fatty acids, can provide a light stripping effect, that is, promote the skin layer of aging cells to shed.
Safety and precautions: Although 4-n-butyl-m-cinechol is generally considered harmless, because it is irritating, allergy testing is recommended before use, and sun protection is recommended when using during the day. Some people may be intolerant to it, and it is necessary to gradually build tolerance when using it to prevent allergic reactions.
4. Whitening skin:
4-butylresorcinol can inhibit the activity of tyrosinase and promote the secretion of melanin. When melanin is formed, it can also inhibit the transfer of melanin to the stratum corneum cells, so as to effectively achieve the whitening effect. In addition, this ingredient can also reduce the acne marks caused by melanin deposit.
5 Reduce color spots:
4-butylresorcinol can whiten spots by inhibiting the activity of "tyrosinase" and "dihydroxyindole carboxylic acid oxidase (TRP-1)". As the substrate of enzyme, 4-butylresorcinol competes for the active site of tyrosinase, thus achieving the inhibition of tyrosinase. 4-butylresorcinol has strong tyrosinase inhibition ability, and also has the effect of inhibiting TRP-1 activity.
6 Prevent photoaging:
4-butylresorcin has a strong protective effect on DNA damage induced by H2O2. It is proved to have anti-saccharification effect. In the three processes of melanin synthesis, 4-butylresorcinol not only has a very important inhibitory effect on tyrosinase activity, but also has a synergistic effect on whitening activity during the process.
