Glycyrrhetinic Acid 98%

Glycyrrhetinic acid 

It is a natural compound derived from the root of Glycyrrhiza glabra. The main components of glycyrrhetinic acid are 3 β-hydroxy-11-oxo-18β, 20 β-oleane-12-enoic acid ,Licorice is a kind of widely used traditional Chinese medicine, which has many pharmacological activities,Glycyrrhetinic acid is white crystalline powder; Odorless, tasteless. Soluble in pyridine, soluble in ethanol or chloroform, slightly soluble in gasoline or ether, insoluble in water

Glycyrrhetinic Acid

CAS number 471-53-4 

Molecular weight 470.684

Density 1.1±0.1 g/cm3 

Boiling point 588.3±50.0 °C at 760 mmHg

Molecular formula C30H46O4 

Melting point 292-295 ºC

Flash point 323.7±26.6 °C

Function and Application

1. Anti-inflammatory and anti-inflammatory effects

Glycyrrhetinic acid has significant anti-inflammatory and anti-inflammatory effects, which can inhibit a variety of acute inflammatory responses and antagonize the effects of inflammatory mediators such as histamine and 5-hydroxytryptamine, thereby reducing inflammatory symptoms.

2. Anti-allergic effect

Glycyrrhetinic acid also has an anti-allergic effect, which can inhibit capillary permeability and reduce cell responsiveness to stimulation.

3. Antibacterial and antitumor effects

Glycyrrhetinic acid has antibacterial and anti-tumor effects, and can be made into anti-inflammatory and anti-allergic preparations for the treatment of rheumatoid arthritis, asthma, allergic and occupational rash, eczema, psoriasis, ear, nose and throat inflammation and ulcers

4. Beauty and skin care function

In the cosmetics industry, glycyrrhetinic acid is used as a skin conditioner, which has anti-inflammatory, anti-allergy and antibacterial effects. It can regulate the immune function of the skin, enhance the skin's resistance to disease, eliminate inflammation, prevent allergies, and clean the skin. In addition, glycyrrhetinic acid can also effectively inhibit the activation of tyrosinase, prevent the production of melanin, and have whitening effect.

5. Adrenocorticoid-like effects

Glycyrrhetinic acid has an adrenocorticoid-like effect and can be used to treat adrenal hypocorticosis (Addisonian disease) and has a diuretic effect.

6. Detoxification

Glycyrrhetinic acid and its metabolites are able to inhibit the conversion of "active" cortisol to "inactive" cortisone in the kidneys, which helps to increase cortisol levels, thereby strengthening the body's resistance