S-Adenosyl-L-methionine Disulfate Tosylate CAS No:97540-22-2

S-Adenosylmethionine (SAM) 

It was first discovered in 1952 by the Italian G.L. antoni. 

It is made of adenosine triphosphate (Adenosinetriphosphate, ATP) and adenosine methionine (methionine) in methionine transferase (Methionineadenosyltransferase) under the action of composite

Medicinal related Function & Application

1.Liver disease:

In the liver, the fluidity of liver cell membrane is regulated by methylation of plasma membrane phospholipids, and the synthesis of detoxification process substances is promoted by transthioylation. Protects against alcohol, drugs and cytokines

2.Damage to the liver:

Prevent cholestasis; 

Prevention of chronic active hepatitis and other factors caused by liver damage, but also to make various causes of abnormal liver function into normal.

3.Emotional dysregulation:

Anti-depression, the effect is better than conventional clinical drugs, and fewer side effects. May increase the transmitter associated with mood.

4.Osteoporosis:

It has been shown in many research articles to be effective in the treatment of osteoporosis.

5.Helpful for AIDS treatment:

In recent years, it has been reported that it can inhibit the proliferation of retroviruses (such as HIV) in vitro, and has been applied to the combination therapy of AIDS patients.

6. Applications in other aspects

As a nutritional supplement:

The use of SAM for therapeutic purposes has increased with the increase in public consumption of nutritional supplements, especially after the passage of the Nutritional Supplement Health and Education Act of 1999, which allowed the use and distribution of SAM as a food additive sold over the counter.

7.As a fine chemical intermediate:

S-adenosylmethionine p-toluenesulfonic acid sulfate is an important fine chemical intermediate, which can be widely used in the synthesis of medicine, pesticides, dyes, bioengineering and polyester compounds due to its many active sites in its molecular structure. In industry, it can also be used as an organic synthetic intermediate, solvent, fragrance, with a strong aroma of Holly oil and Yunanga oil, used to prepare perfume flavors and artificial essential oils.