Alpha-Ketoglutaric Acid
α-ketoglutaric acid (a-KG)is an important biological molecule, one of the important intermediates in the tricarboxylic acid cycle,and is a nitrogen transporter and a symbiotic substance in molecular oxidation. It plays an important role in the metabolism of microbial cells,and is also an important precursor for the synthesis of many amino acids and proteins.α-ketoglutaric acid can be used as a nutrient fortifier and as a component of sports nutrition drinks.It can also be used as organic intermediates, biochemical reagents and matching reagents to measure liver function,and physical strengthening supplements.
Product Name: | Alpha-Ketoglutaric Acid |
Other name: | AKG, Ca AKG |
Spec./Purity: | 98% |
EINECS: | 275-843-2 |
Appearance: | White powder |
CAS NO. | 71686-01-6 |
Molecular Formula | C5H4O5CA |
Shelf Life: | 2 Years |
Function: | Anti-aging, anti-fatigue, enhance bone density, promote animal growth, inhibit bacteria and relieve itching |
Application: | Cosmetics, health products, pharmaceuticals, animal feed additives, cosmetic medicine |
NO | Product Name | Cas No | Ratio |
1 | Alpha-Ketoglutaric Acid | 328-50-7 |
|
2 | L-Ornithine Alpha-Ketoglutaric Acid | 5144-42-3 | OAKG 2:1 |
3 | L-Ornithine Alpha-Ketoglutaric Acid | 5191-97-9 | OAKG 1:1 |
4 | L-Arginine Alpha-Ketoglutaric Acid | 5256-76-8 | AAKG 2:1 |
5 | L-Arginine Alpha-Ketoglutaric Acid | 16856-18-1 | AAKG 1:1 |
Alpha-Ketoglutaric Acid Function:
1. Energy Metabolism:
Alpha-Ketoglutaric Acid AKG is a key intermediate product of the tricarboxylic acid cycle, through a series of reactions to completely oxidize and decompose nutrients such as sugar, fat and protein, generate carbon dioxide and water, and produce a lot of energy, in the form of ATP, to provide power for cell activities.
2. Amino Acid Metabolism:
Alpha-Ketoglutaric Acid AKG Participating in transamination, amino exchange with a variety of amino acids to generate corresponding amino acids and glutamic acid,
which contributes to the balance of amino acid synthesis and catabolism in the body, and provides a way for the synthesis of non-essential amino acids.
At the same time, it can combine with ammonia to produce glutamic acid, which converts excess ammonia in the body into a non-toxic form and is discharged in the urine, playing a detoxification role.
3. Improve Cognitive Function:
Alpha-Ketoglutaric Acid AKG may have potential therapeutic effects on neurological diseases, such as improving cognitive function,
which may be related to its involvement in neurotransmitter synthesis and regulation of nerve cell metabolism.
4. Myocardial Protection:
Alpha-Ketoglutaric Acid AKG has certain benefits on the cardiovascular system, and may help protect cardiomyocytes, reduce cardiomyocyte damage and maintain normal cardiac function by regulating energy metabolism and intracellular signaling pathways in cases of myocardial ischemia-reperfusion injury.
5. Sports and Fitness:
In health care products,Alpha-Ketoglutaric Acid AKG helps to improve the body's energy level, enhance exercise endurance, promote muscle synthesis,
help athletes and fitness enthusiasts to improve sports performance, reduce fatigue, and accelerate recovery.
6. Plant Growth Regulation:
As a plant growth regulator in the agricultural field, Alpha-Ketoglutaric Acid AKG can promote plant growth and development, improve plant stress resistance,
and enhance plant tolerance to drought, salt and alkali and other adversities, thereby improving crop yield and quality.
Alpha-Ketoglutaric Acid Application:
1. Medical Field:
As a drug intermediate, Alpha-Ketoglutaric Acid AKG is used to synthesize some compounds with therapeutic effects. For example,
Alpha-Ketoglutaric Acid AKG can be used to synthesize certain antibiotics, vitamins and amino acids.
2. Health Care Products:
Alpha-Ketoglutaric Acid AKG is often added to some health products. Due to its important role in energy metabolism and amino acid metabolism,
taking health products containing alpha-ketoglutaric acid may help to improve the body's energy level,
strengthen immunity, promote muscle synthesis, etc., suitable for athletes, fitness enthusiasts,
and some people who are weak and need to supplement nutrition.
3. Agriculture:
Alpha-Ketoglutaric Acid AKG can be used as a plant growth regulator. The appropriate use of alpha-ketoglutaric acid can promote the growth
and development of plants and improve the stress resistance of plants,
such as enhancing the tolerance of plants to drought, salt and alkali stress conditions, thereby improving the yield and quality of crops.
4. Microbial Fermentation Field:
In the microbial fermentation process, Alpha-Ketoglutaric Acid AKG can be used as an important carbon and nitrogen source for the cultivation of some microorganisms
and the production of amino acids, enzymes and other biological products.
At the same time, Alpha-Ketoglutaric Acid AKG can also regulate the metabolic pathways of microorganisms and increase the yield of target products.
