Gentiopicroside
Gentiaceae plant. Dried roots and rhizomes. Gentian has gallbladder and resistance
Inflammation, stomach, blood pressure and other effects. Gentiana mainly contains iridoid glycosides,
of which gentiopicrin is the main active component.
Gentiopicroside
CAS number 20831-76-9
Molecular weight 356.325
Density 1.5±0.1 g/cm3
Boiling point 667.8±55.0 °C at 760 mmHg
Molecular formula C16H20O9
Melting point of 191°C
Flash point 247.1±25.0 °C
The Function Of Gentiopicroside
1. Anti-liver fibrosis and cirrhosis:
Gentian Extract Gentiopicroside can inhibit the activation of hepatic stellate cells, reduce the occurrence of liver fibrosis, and thus prevent the development of liver cirrhosis. It can inhibit the proliferation, migration and transformation of hepatic stellate cells to play an anti-fibrosis role, and also inhibit the production of inflammatory cytokines and chemokines in hepatic stellate cells to reduce liver inflammation.
2. Regulate liver cell function:
Gentian Extract Gentiopicroside can inhibit cell activation and reduce liver inflammation.
3. Inhibit liver T cell infiltration:
Gentian Extract Gentiopicroside can inhibit the infiltration of liver T cells, thereby reducing liver-related symptoms.
5. Protect your liver:
Gentian Extract Gentiopicroside can improve the imbalance of lipid metabolism caused by long-term alcoholism, reduce fat deposition, and have a certain effect on alcoholic fatty liver, non-alcoholic fatty liver, etc., and also prevent mild liver fibrosis caused by liver steatosis, which is beneficial to protect the liver.
6. Inhibit tumor cell proliferation:
Gentian Extract Gentiopicroside can inhibit the expression of cyclin and thus inhibit the proliferation of tumor cells. In addition, Gentian Extract Gentiopicroside can inhibit the spread of tumor cells by inducing cell apoptosis and inhibiting tumor angiogenesis.
7. Reverse multidrug resistance in tumor cells:
Gentian Extract Gentiopicroside can reverse the multidrug resistance of tumor cells by inhibiting the expression of P-glycoprotein and MRP1, and can be used in combination with other anti-tumor drugs to improve the anti-tumor efficacy.
8 Immune regulatory effects:
Gentian Extract Gentiopicroside can activate T cells and natural killer cells, which play a key role in anti-tumor immune response.
9. Antidepressant effects:
Gentian Extract Gentiopicroside is helpful to reverse the damage of cortisol to the body, so it has a certain effect in reducing depressive symptoms, such as low mood, loss of interest, slow thinking, and decreased attention.
10. Anti-inflammatory effect:
Gentian Extract Gentiopicroside is helpful to relieve allergic asthma, osteoarthritis, gastritis and other discomfort, and has a certain anti-inflammatory effect.
11. Improvement of diabetes and osteoporosis:
Gentian Extract Gentiopicroside is helpful to improve diabetes, osteoporosis and so on.
12. Effect on bile secretion and gallbladder contraction:
Gentian Extract Gentiopicroside can increase bile secretion and promote gallbladder contraction.
13 Excitatory effects on the central nervous system:
Gentian Extract Gentiopicroside has an excitatory effect on the central nervous system.
14. Application in analgesia and arthritis drugs:
Gentian Extract Gentiopicroside containing more than 50% of gentiopicroside can be used in the preparation
of drugs for the treatment of arthritis and in analgesics.
