Gromwell Extract Shikonin 30%

Gromwell Extract Shikonin

Gromwell Extract Shikonin an active ingredient extracted from the roots of Lithospermum erythrorhizon, is also present in other plants such as Arnebia euchroma. It is a purple flake crystal or crystalline powder, used in the treatment of acute jaundice or non-jaundice hepatitis, chronic hepatitis, flat warts, etc., has a good effect. It is also effective against cirrhosis (ascites) and common warts.

Gromwell Extract Shikonin

CAS number 517-88-4 

Molecular weight 288.295

Density 1.4±0.1 g/cm3 

Boiling point 567.4±50.0 °C at 760 mmHg

Molecular formula C16H16O5 

Melting point 149°

Flash point 311.0±26.6 °C

Place of Origin:China
Packaging:1KG/Bag. 25kg/drums
The private label service:1kg/cans 500g/1kg/ Aluminum foil bag
the Capsules OEM service; 0# Capsules 500mg/pcs. 2000pcs/kg in Vacuum bag

Function and application;

1. Inhibit the release of inflammatory mediators:

Gromwell Extract Shikonin  inhibits the release of inflammatory mediators TNF-α from macrophages 

and reduces inflammation by inhibiting the transport of NF-κBp65 from the cytoplasm to the nucleus.

2. Increase the expression of specific proteins:

Gromwell Extract Shikonin can increase the expression of I-κBα and ubiquitination protein in macrophages.

3. Antibacterial effect

Gromwell Extract Shikonin has antibacterial properties and can fight against a variety of pathogenic microorganisms. For example, Gromwell Extract Shikonin can effectively inhibit the growth of Staphylococcus aureus.

4. Promote wound healing

Gromwell Extract Shikonin has also shown remarkable results in promoting wound healing.

5. Promote granulation tissue growth:

Gromwell Extract Shikonin , the wound granulation tissue grew actively, and the color was red and soft.

6. Accelerate tissue repair:

Gromwell Extract Shikonin, the wound tissue cells proliferated vigorously and new blood vessels were formed. After 21 days, the wound tissue tended to epithelialize.

7. Antioxidant and anti-tumor effects

Gromwell Extract Shikonin not only has antioxidant effects, but also scour free radicals and has shown potential in anti-cancer, being able to induce apoptotic cells and necrotic cell death. Clinical studies have shown that it can be used to treat acute and chronic hepatitis and cirrhosis of the liver.

8. Other benefits

Gromwell Extract Shikonin also has a variety of beauty values such as acne, anti-inflammatory, skin repair, fade scars, and can be used as a natural pigment in the pharmaceutical, food and cosmetic industries