Hyaluronic Acid 99%
Hyaluronic acid sodium salt (HA) is a kind of polymer mucopolysaccharide with D-n-acetylglucosamine and
D-glucuronic acid as its structural units.
It is widely used in medicine, health food and cosmetics and other fields.
Name Hyaluronic acid
CAS Number 9004-61-9
Molecular Weight 379.32 (monomer)
Density 1.8±0.1 g/cm3
Boiling point 1274.4±65.0 °C at 760 mmHg
Molecular formula (C14H21NO11)n
Melting point N/A
Flash point 724.5±34.3 °C
Specification of Hyaluronic acid in cosmetic.
Molecular Weight:≤ 1 MDa
Molecular Weight:1~10 MDa
Molecular Weight:10-60 MDa
Molecular Weight:60-100 MDa
Molecular Weight:100-160 MDa
Molecular Weight:160-200 MDa
Molecular Weight:200 MDa
No. | Item | Specification |
1 | Identification | Sodium Identify Reaction | Positive |
2 | Characters | White Powder orGranules |
3 | Glucuronic Acid | ≥45.0% |
4 | Sodium Hyaluronate | ≥93.0% |
5 | pH (0.5% Water Solution) | 5.5 ~ 8.0 |
6 | Limiting Viscosity | 2.86 ~ 11.57dL/g |
7 | Molecular Weight | 0.1 ~ 0.6MDa |
8 | Transparency (0.5% Water Solution) | ≥99.0% |
9 | 280nm absorbance (0.5% Water Solution) | ≤0.25 |
10 | 260nm absorbance (0.33%, 0.9% sodium chloride solution) | ≤0.5 |
11 | Residue on Ignition | ≤20.0% |
12 | Loss on Drying | ≤10.0% |
13 | Protein | ≤0.1% |
Function of Hyaluronic Acid
1.Moisturizing effect:
Sodium hyaluronate has excellent water absorption due to its ability to bind a large number of water molecules through hydrogen bonding,
and its theoretical water retention value can reach 500ml/g. It is widely distributed in the dermis and acts as a 'reservoir' to
help the skin retain moisture, prevent and improve wrinkles, and delay aging.
2.Repair damaged skin:
Sodium hyaluronate can promote epidermal cell proliferation and division, and remove oxygen free radicals,
thereby promoting the regeneration of the injured skin.
This has a repairing effect on skin damage caused by environmental factors such as sun exposure.
3.Skin conditioner:
Sodium hyaluronate, as a skin conditioner, can improve skin nutrition metabolism, make skin tender, smooth, wrinkle free,
increase elasticity, and prevent aging.
It can also be used as a transdermal absorption promoter, and when used in combination with other nutrients,
it can play a more desirable effect to promote nutrient absorption
4.Thickening and stability:
Sodium hyaluronate has a high viscosity in aqueous solution, and its 1% aqueous solution is gel-like,
which can play a thickening and stabilizing role in cosmetics.
5.Lubrication and film formation:
Sodium hyaluronate is a polymer with strong lubrication and film formation.
Skin care products containing sodium hyaluronate have obvious lubrication and good hand feel when applied,
and can form a protective film on the skin surface, making the skin feel smooth and moisture5.
6.Anti-wrinkle effect:
sodium hyaluronate can penetrate into the dermis, regulate skin metabolism, and play a cosmetic and health care role of anti-wrinkle.
7.Alleviating skin aging:
sodium hyaluronate in cosmetics also has the effect of alleviating skin aging, by supplementing the hyaluronic acid in the skin,
it can reduce skin water loss, fine lines, elasticity loss and other problems caused by aging.
