Milk Thistle Extract Silymarin 80%
Milk Thistle Extract Silymarin is an antioxidant derived from a plant called Milk Thistle. Silymarin can stabilize liver cell membrane,
maintain the integrity of liver cells, so that toxins can not penetrate and destroy the liver,
and accelerate the synthesis of liver cell DNA (deoxyribonucleic acid),
can prevent cirrhosis, fatty liver, cholangitis, psoriasis and other diseases, and has liver cancer, prostate cancer,breast cancer and cervical cancer cell growth and differentiation inhibition.
Milk Thistle Extract Silymarin is the most effective flavonoid for liver disease found in the world.
Chemical Information
| Extract Name | Milk Thistle Extract | Active Ingredient | Silymarin |
| CAS No | 65666-07-1 | Molecular formula | C25H22O10 |
| Molecular weight | 482.436 | Boiling point | 793.0±60.0 °C at 760 mmHg |
| Flash point | 274.5±26.4 °C | Density | 1.5±0.1 g/cm3 |
| Melting Point | / | MSDS/ COA | Available |
Certificate Of Analysis
| No | Test items | Specification & Standards | Results |
| 1 | Apperance | Amorphous Powder | Conforms |
| 2 | Colour | Yellow to Yellowish-Brown | Conforms |
| 3 | Odour | Slight, Specific | Conforms |
| 4 | Solubility | in Methanol and Acetone | Conforms |
| 5 | SulphatedAsh | NMT 0.5% | Conforms |
| 6 | Heavy metals | NMT 10 PPM | Conforms |
| 7 | Loss On Drying | NMT 5.0% | Conforms |
| 8 | Powder size | NLT 90% 80mesh | Conforms |
9 | Silymarin ( UV) Silymarin (HPLC) Silybin A.B. Isosilybin A.B. Silydianin&Silychristin | NLT 80%
NLT 50% | 88.9% 52. 1% 33.5% 5.7% 12.9% |
10 | Residual Solvents N-hexane Methanol Acetone Ethyl Acetate Ethanol |
NMT 0.029% NMT 0.3% NMT 0.5% NMT 0.5% NMT 0.5% |
Conforms |
11 | Microbiological Quality (Total viable aerobic count) Total bacterial count Moulds & Yeasts Escherichia coli Salmonellaspecies |
NMT 1,000.0 CFU/g NMT 100.0 CFU/g Not detected Not detected |
Conforms |
The others Specification Recommend
| Extract | Specification |
Acetone | Silybin +Isosilybin 30 HPLC Silybin30%HPLC Silymarin 40% HPLC Silymarin 50% HPLC Silymarin 55% HPLC Silymarin 60% HPLC Silymarin 80% UV Silybin +Isosilybin 30 HPLC Silybin30%HPLC |
Ethanol | Silymarin 40% HPLC
Silymarin 50% HPLC Silymarin 60% HPLC |
Ethyl Acetate
| Silymarin 40% HPLC Silymarin 45% HPLC Silymarin 50% HPLC Silymarin 60% HPLC |
Water soluble silymarin
| Silymarin 40% UV Silymarin 45% UV Silymarin 50% UV |
Difference Specification & Service
| Milk Thistle Powder | 80-100mesh with the TLC |
| Milk Thistle Extract | 10:1 With the TLC Silymarin 40% 80% UV HPLC |
| Milk Thistle Extract Capsules | 0# Capsules 500mg/pcs. 2000pcs/kg in Vacuum bag |
| The private label service | 1kg/cans 500g/1kg/ Aluminum foil bag |
| Nomal Packaging | 1KG/Bag. 25kg/drums |
Milk Thistle Extract Function:
1. Anti-oxidative damage:
Milk Thistle Extract Silymarin can eliminate free radicals (such as hydroxyl radicals and superoxide anions), reduce the damage of liver cells caused by oxidative stress, and delay the aging and apoptosis of liver cells.
2. Inhibit liver fibrosis:
Milk Thistle Extract Silymarin can inhibit the activation of hepatic stellate cells, reduce the synthesis of collagen, prevent the process of liver fibrosis, and has a certain improvement effect on chronic hepatitis, liver cirrhosis, etc.
3. Promote hepatocyte repair:
Milk Thistle Extract Silymarin helps repair damaged liver tissues and restore liver function (such as improving indicators like elevated transaminases) by enhancing the regenerative ability of liver cells.
4. Anti-hepatotoxin:
Milk Thistle Extract Silymarin can inhibit the damage to the liver caused by alcohol, drugs (such as acetaminophen), and chemical toxins (such as aflatoxin), and reduce the accumulation of toxins in liver cells.
5. Improve lipid metabolism:
Milk Thistle Extract Silymarin can reduce the levels of cholesterol and triglycerides in the blood, inhibit the accumulation of fat in the liver (such as fatty liver), regulate lipoprotein metabolism at the same time, and reduce the risk of atherosclerosis.
6. Enhance antioxidant capacity:
Milk Thistle Extract Silymarin enhances the overall antioxidant defense system by activating antioxidant enzymes in the body (such as glutathione peroxidase), combating systemic chronic inflammation and oxidation-related diseases (such as diabetes and cardiovascular diseases).
7. Inhibition of inflammatory factors:
Milk Thistle Extract Silymarin can down-regulate the expression of inflammatory mediators (such as TNF-α and IL-6) in the liver, alleviate the liver inflammatory response, and has a alleviating effect on inflammatory liver diseases such as non-alcoholic steatohepatitis (NASH).
8. Regulate the function of immune cells:
Milk Thistle Extract Silymarin may balance the immune response and reduce abnormal immune attacks in autoimmune liver diseases (such as autoimmune hepatitis) by influencing the activity of immune cells (such as T cells and macrophages).
9. Protect the cardiovascular system:
Milk Thistle Extract Silymarin improves vascular endothelial function through antioxidation and lipid regulation, and reduces the risk of cardiovascular diseases such as hypertension and coronary heart disease.
10. Auxiliary anti-tumor:
Milk Thistle Extract Silymarin may inhibit the proliferation of tumor cells (such as liver cancer and breast cancer cells) and induce tumor cell apoptosis, but its clinical effect still needs to be verified by more studies.
11. Improve complications of diabetes:
Milk Thistle Extract Silymarin can enhance insulin sensitivity, improve glucose metabolism, and at the same time alleviate oxidative stress and vascular damage in diabetic patients, reducing the risk of complications such as retinopathy and neuropathy.
